The human gene driven by the CAG promoter was cloned downstream of a floxed neo cassette and 4 polyadenylation sequences (STOP signal). Expression of the human gene can only be achieved by cre-mediated removal of the floxed neo STOP cassette. (J:143278, J:143859)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
Insertion
--
--
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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