A loxP site was inserted into the 5' untranslated region and an frt-flanked neo cassette with a loxP site was inserted into intron 3. Germ line, flp mediated recombination was used to remove the neo cassette leaving exons 1 through 3 floxed. (J:143472)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count