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The chicken beta-actin promoter with the Rous sarcoma virus-long terminal repeat from the miw vector was used to drive ubiquitous expression of a fusion gene encoding the laminin alpha chain and first 2 laminin-type globular (LG) modules from Lama5 and LG modules 3-5 of human LAMA1. The line produced expresses the transgene at a higher level than in mice carrying Tg(CAG-Lama5*G2/LAMA1)1Jhm. (J:119297)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
