A floxed neomycin expression cassette was inserted into intron 9 and a stop codon was inserted in exon 9. This results in an incomplete and misfolded D3 segment in the mesenchymal or c isoform. Chimeric mice were mated to Tg(ACTB-cre)2Mrt mice to excise the floxed neo cassette. (J:142946)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count