A floxed neomycin expression cassette was inserted into intron 9 and a stop codon was inserted in exon 9. This results in an incomplete and misfolded D3 segment in the mesenchymal or c isoform. Chimeric mice were mated to Tg(ACTB-cre)2Mrt mice to excise the floxed neo cassette. (J:142946)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
Insertion
--
1
39
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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