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The mouse promoter was used to drive early hematopoietic cell-specific expression of human SET intron 7-8 fused to NUP214 intron 17-18. This fusion mimics the human translocation t(9,9)(q32;34) identified in patients with acute undifferentiated leukemia. Three lines were created (2945, 2969, and 2971) with line 2969 selected as the representative line. (J:142938)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
