A loxP site was inserted upstream of exon 11 (exon 10 in legacy nomenclature numbering) and a floxed neo cassette was inserted downstream of exon 11. Cre-mediated recombination was used to remove the neo cassette leaving exon 11 floxed. (J:142723)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count