Exons 2 and 3 were flanked by loxP sites and an frt-flanked neo cassette was inserted upstream of exon 2. Following recombination, a functional protein may be expressed. (J:142827)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count