A floxed construct containing lacZ and an FRT flanked neomycin selection cassette was inserted at the second ATG in the first coding exon. Expression of the lacZ reporter is very low. RT-PCR indicated the absence of mRNA and Western blot analysis indicated that no protein is produced. (J:142596)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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