A cassette containing an IRES-ALPP reporter gene and floxed neo gene was inserted into exon 2. Germ line, cre mediated recombination was used to remove the neo cassette. The absence of transcript expression was confirmed by QPCR of liver extracts. (J:142722)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count