A construct containing approximately 6 kb of the mouse Cyp21a1 promoter attached to the mouse Apoe gene was used for injection into fertilized FVB/N oocytes. Ten independent founder lines were generated. Line 614 is representative of high expressing Apoe lines (lines 614, 615, and 616). (J:130658)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count