Exon 1 is flanked by loxP sites and an frt-flanked PGK-neomycin selection cassette was inserted downstream of exon 1. The PGK-neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:280238)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count