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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
Amyotrophic Lateral Sclerosis 1
USH2A c.8559-2A>G
Cystic Fibrosis
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Gene editing
Mir133a-2
tm1.1Eno
Alias:
Mirn133a-2
ko
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Basic Information
Phenotypes
References Literature
The 108 bp pre-miR stem loop was replaced by an FRT flanked neomycin resistance cassette. Mice derived from correctly targeted ES cells were crossed to Tg(ACTFLPe)9205Dym mice to excise the neomycin selection cassette. (J:142220)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
3822158
129S/SvEv
Targeted
Insertion, Intragenic deletion
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5
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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