The 68 bp pre-miR stem loop found in intron 23 of Mib1 was replaced by an FRT flanked neomycin resistance cassette. Mib1 expression is not affected. Mice derived from correctly targeted ES cells were crossed to Tg(ACTFLPe)9205Dym mice to excise the neomycin selection cassette. (J:142220)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S/SvEv
Targeted
Insertion, Intragenic deletion
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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