A 355 bp fragment including 73 bp of intron 6, all of exon 7, and 69 bp of intron 7 plus an IRES betageo cassette were deleted via Cre mediated recombination of Shmt1tm1Stov. Immunoblot analysis confirms absence of protein expression in tissues from homozygous mice. (J:141998)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
Insertion, Intragenic deletion
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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