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The transgene contains the coding sequences for the hepatitis C virus (HCV) envelope proteins, E1 and E2, downstream of the enhancer and promoter from the HBx antigen gene of hepatitis B virus (HBV) and followed by the HBX polyadenylation signal. Both HCV envelope proteins are expressed in organs of transgenic mice, most strongly in the liver, where they occur in association with one another and primarily in the cytoplasm of hepatocytes surrounding the hepatic central veins. (J:129014)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
