A floxed neo cassette was inserted upstream of exon 5 and a single loxP site was inserted downstream of exon 5. The neo cassette was then removed by Cre mediated recombination leaving exon 5 floxed. (J:124926, J:141850)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count