The gene trap is inserted in the first intron at the 3' end. The last 754 nucleotides of the intron and the first nucleotide of exon 2 are deleted. The splice acceptor for exon 2 is lost. In addition to a transcript containing gene trap vector sequences, a transcript resulting from splicing exon 1 to exon 3 is expressed. (J:141678)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count