A neomycin resistance cassette replaced part of exon 1, exons 2-5 and part of exon 6. Quantitative RT-PCR of splenocyte extracts confirmed gene inactivation without affecting expression of the nearby genes Tnfsf12 and Senp3. (J:141374)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count