The targeting vector MHPP80o18, which contains an agouti minigene and puromycin resistance cassette, was inserted between exons 7 and 10 via gap repair and disrupts exons 12 through 16 while exons 1 through 10 remain intact. This allele is hypomorphic as determined by western blot analysis of heterozygous tissue extracts. (J:141467)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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