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EN
A NcoI-NcoI fragment at the upstream portion of the open reading frame was replaced with an in-frame LacZ-hprt reporter gene. Gene inactivation was confirmed by a lack of protein found on immunoblotting of brain extracts from E12.5 homozygotes. LacZ expression was detected in the neuroepithelium and mysenchymal cells of both the forebrain and hindbrain of E9 homozygote embryos. (J:141306, J:283453)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
