Mice carrying the Ccm2tm1Kwhi allele that has exons 3-10 floxed were crossed with Hprttm1(cre)Mnn. Removal of the floxed exons from the germline was confirmed by genomic PCR on the offspring. This is considered a null allele. (J:146527)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count