A loxP site was inserted upstream of exon 3 and a neomycin resistance cassette followed by a loxP site and then an EGFP gene were all inserted downstream of the last exon (exon 10). Correct targeting was confirmed by genomic PCR. (J:146527)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count