The retrovirus gene trap vector GTR1.3 containing a puro gene, a lacZ gene, a Pol2 gene and a neo cassette was inserted into intron 16. The fusion transcript lacks exon 17 and encodes a fusion protein that replaces the last 49 amino acids with 137 irrelevant residues. (J:137511, J:141099)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/Sv
Gene trapped
Insertion of gene trap vector
--
1
2
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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