Coding sequence for murine Crh gene and an IRES-lacZ sequence was preceded by a loxP-flanked transcriptional terminator and then was knocked into the Gt(ROSA)26Sor locus. Upon cre recombinase expression and excision of the loxP-stop sequence, the Crh and lacZ reporter gene are predicted to be expressed. (J:149207)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count