The entire coding sequence was replaced with a lacZ reporter and PGK-neo cassette. RT-PCR analysis confirmed the absence of expression mRNA in homozygotes. LacZ expression was detected in the hippocampus, posterior commissure, habenula, cerebellum, olfactory glomeruli, and dorsal tegmental nucleus. (J:140787)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count