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A recombined Tcra gene associated with Valpha19 NK T cells was used in a transgene construct. The Valpha19-Jalpha26 (AV19-AJ33) transgene with the endogenous TCR alpha promoter and enhancer were injected into TCR Ca-deficient fertilized eggs. T cells expressing the transgenic TCR-alpha chain were detected in the liver. (J:140924)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
