A loxP site was inserted 5' to exon 2, and a loxP- and FRT-flanked neomycin cassette was placed 3' to exon 4. For this allele (delta N), the FRT-flanked neomcycin cassette was deleted by crossing the mice with a widely-expressed Flp strain of unknown genetic background, leaving a single residual FRT site and exons 2-4 flanked by loxP sites. (J:237954)
Basic Information
(C57BL/6NTac x 129S6/SvEvTac)F1
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count