A loxP site was inserted 5' to exon 2, and a loxP- and FRT-flanked neomycin cassette was placed 3' to exon 4. For this allele (delta N), the FRT-flanked neomcycin cassette was deleted by crossing the mice with a widely-expressed Flp strain of unknown genetic background, leaving a single residual FRT site and exons 2-4 flanked by loxP sites. (J:237954)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NTac x 129S6/SvEvTac)F1
Targeted
Insertion, Intragenic deletion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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