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LoxP sites were placed on either side of exons 22-24 (encoding the S5/S6 transmembrane domains) and an FRT-flanked neomycin resistance cassette inserted in the opposite transcriptional orientation in intron 24. The neomycin cassette was excised by crossing these mice to a Gt(ROSA)26Sor-driven Flp strain on a 129S4/SvJaeSor. (J:169738)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
