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The entire JHwas replaced with a rearranged VDJ exon carrying a translational stop codon at amino acid position 3 of the leader peptide and a floxed neomycin resistance cassette. Mutant mice were crossed with Tg(EIIa-cre)C5379Lmgd mice resulting in excision of the selection cassette. (J:140486)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
