A loxP site was inserted upstream of exon 20 and loxP-flanked neomycin cassette was inserted downstream of exon 20. Correct targeting was confirmed by genomic PCR. The floxed exon contains the polyadenylation signals so that upon expression of cre recombinase, the resulting transcipts derived from this locus would be truncated and have a shorter half-life. (J:140205)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion
--
1
9
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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