The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 7346bp between positions 24597866-24605211 of Chromosome 6 (Build GRCm39). The entire gene starting at the translational start site and ending at the translational stop site, was replaced with the lacZ reporter cassette. Western blot confirmed complete loss of protein in the left ventricle. (J:136110, J:227272)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
Insertion, Intragenic deletion
--
1
2
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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