The genomic region containing part of exon 2 through part of exon 5 was replaced with and IRES-tau, lacZ and floxed neo cassette. The absence of protein expression was confirmed by immunohistochemistry on nervous tissue and the absence of transcript expression as confirmed by RT-PCR analysis on brain and regenerating liver extracts. (J:140235)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intragenic deletion
--
1
--
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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