A loxP site was inserted upstream of exon 2 and a frt-flanked neomycin cassette followed by another loxP site was placed downstream of exon 3. Endogenous gene expression was unaffected in homozygous mice as determined by flow cytometry on freshly isolated lymphocytes. (J:140085)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count