RNA was isolated from an I-Ab restricted, Beta-gal specific CD4+ T cell clone. The variable domains for both the Tcra and Tcrb genes were cloned into TCR cassette vectors and co-injected into fertilized embryos. Transgenic mice produce T cells that recognize peptides from the product of the LacZ gene. (J:140121, J:140160)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count