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Vk167/PEPS is a transgene with a truncated region upstream of the promoter. The Igk (immunoglobulin kappa) sequence was further modified in the current strain through the insertion of 5 tandem repeats of a 20-bp adenine/thymine (A/T) fragment near the 3' end of the variable region. The inserted sequence is identical to the insert in the TgA line but is in the reverse orientation. This "TgT" line has an A/T sequence comparable to that found in line "TgC" without the single cytosine:guanine (C:G) insert. (J:139793)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
