Tg(Fabp7-cre,-lacZ)3Gtm

A 1.6 kb fragment of murine Fabp7 drives expression of a nuclear targeted cre. The transgene also contains and IRES-lacZ sequence. LacZ expression is seen in the ventricular region of the spinal cord and in the hindbrain at E9.5, in thedorsal portion of the rostral neuroepithelium and in the midbrain at E10.5, extending into the ventricular/subventricular regions of the brain by E12.5, and in the ependymal cell layer of the ventricle with distinct labeling in the subventricular zone in young adults. No expression is detected in other organ systems. Three lines were generated with lines 2 and 3 having identical expression patterns. (J:139866)