A neomycin resistance cassette replaced exon 1 and part of exon 2. Correct targeting was established by Southern blotting. Immunofluorescence staining of inflamed footpads confirmed a lack of gene expression (J:138942)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count