A cassette containing a puromycin resistance gene, an Hprt minigene, and an agouti minigene was inserted 3' of exon 6. Following this insert, exons 3-6 were duplicated. Northern blot analysis indicated the complete absensence of mRNA transcribed from this allele in liver RNA. (J:138734)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
Insertion
--
1
2
13

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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