A floxed neo cassette was inserted upstream of exon 15 and an additional loxP site was inserted downstream of exon 17. Germ line, cre mediated recombination was used to remove the neo cassette. (J:139257)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count