The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1620bp between positions 30841100-30842719 of Chromosome 11 (Build GRCm39). RT-qPCR demonstrated the absence of transcripts in retinal samples from homozygous mutant mice. Immunohistochemistry using an anti-GPR75 polyclonal antibody generated against an epitope in the carboxy-terminal tail confirmed the absence of protein in the retina. (J:136110, J:341992)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
Insertion, Intragenic deletion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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