The promoter was used to drive expression of a codon improved cre in the theca/interstitial cells of the ovary and Leydig cells of the testes. Three lines (lines A, B and C) were created. While all lines exhibit gonadal expression, line B and C exhibit extra-gonadal expression. (J:138920)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count