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A floxed neo cassette was inserted 108 bp upstream of the E2f3a start codon, the mouse E2f1 open reading frame including the termination codon replaced the exon 1a open reading frame, and a third loxP site was inserted approximately 300 bp downstream of exon 1a. Western blot analysis in double homozygous MEFs lacking E2f1 wild-type alleles confirmed the expression of E2F1 protein. (J:138289)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
