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The transgene construct contained 1.4 Kb of the H2-Ld promoter driving expression of the human IL6 cDNA which had a 340 bp 3' untranlated region deleted, to increase mRNA stability. A 770 bp fragment of this construct was inserted into the rabbit beta-globin sequence, resulting in a 3.3 kb fragment which was injected into fertilized C57BL/6 eggs. (J:40405)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
