This transgene consists of a 2.2 kb fragment of the bovine rhodopsin promoter driving expression of a full length human VEGFA cDNA followed by an intron and polyA site from the mouse protamine gene. Thirteen to fifteen copies of the transgene were incorporated in this line. MRNA expression analysis detected a modest signal at P7, a strong signal at P14, and only faint expression at 3 months of age in the retinas of hemizygous mice. (J:41411)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
--
Insertion
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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