A cassette containing lacZ gene and frt-flanked puromycin gene and encompassed by a 5' loxJTZ17 site and a 3' lox2272 site was inserted upstream of exon 1. Targeted recombination was performed in cells already containing Spink3tm1Kymm replacing its neo cassette. (J:138347, J:205182)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
Insertion
--
1
5
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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