A cassette containing lacZ gene and frt-flanked puromycin gene and encompassed by a 5' loxJTZ17 site and a 3' lox2272 site was inserted upstream of exon 1. Targeted recombination was performed in cells already containing Spink3tm1Kymm replacing its neo cassette. (J:138347, J:205182)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count