A floxed neo cassette was inserted downstream of exon 3 and an additional loxP site was inserted downstream of exon 6. Germ line, cre-mediated recombination was used to remove the neo cassette leaving exons 4 through 6 floxed. (J:137598)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count