A loxP site was inserted upstream of exon 5 and a floxed neo cassette was inserted downstream of exon 5. Transient cre expression in ES cells was used to remove the neo cassette leaving exon 5 floxed. (J:137631)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count