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EGFP (enhanced green fluorescent protein) cDNA was knocked into the second exon of the gene immediately after the endogenous start codon. A loxP-flanked neomycin resistance cassette was also inserted right after the EGFP sequence. The targeting vector was introduced to an embryonic stem cell line derived from albino C57BL/6 mice. A cross with a C57BL/6 background EIIa-Cre mouse excised the neomycin cassette. (J:156990)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
