Krt33a^Plsh-2Btlr

This mutation, discovered by its visible phenotype among G1 progeny of an ENU-mutagenized male mouse, corresponds to a T-to-C transition at nucleotide position 363 of the gene, in the first of seven total exons. This substitution results in replacement of cysteine by arginine at amino acid position 100 (C100R), in the first linker domain of the keratin protein. (J:137499)