The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 15139bp between positions 141415641-141430779 of Chromosome 4 (Genome Build37). The lacZ reporter gene and neomycin resistance selection cassette replaced the coding sequence. Western blot analysis confirmed the absence of protein expression in bone marrow, spleen and thymus. (J:136110, J:223142, J:228565)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
Insertion, Intragenic deletion
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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