The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 15139bp between positions 141415641-141430779 of Chromosome 4 (Genome Build37). The lacZ reporter gene and neomycin resistance selection cassette replaced the coding sequence. Western blot analysis confirmed the absence of protein expression in bone marrow, spleen and thymus. (J:136110, J:223142, J:228565)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count